ATP1B3 and BAALC

Data Source:
BioGRID (two hybrid)

		ATP1B3	BAALC
Description		ATPase Na+/K+ transporting subunit beta 3	BAALC binder of MAP3K1 and KLF4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Neuron Projection Membrane Raft
	Molecular Function	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 32888494 27863252 28957414) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)	Breast cancer and/or colorectal cancer ( 29698419) Late-onset Alzheimer's disease ( 27770636) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		13 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4	13 interacting genes: AGTR1 AP1G1 ATP1B3 ATXN1 CHD1L CHEK2 CINP MAP3K1 MDFI NAA10 NAA11 OSBPL1A RNF2
Entrez ID		483	79870
HPRD ID		03521	09422
Ensembl ID		ENSG00000069849	ENSG00000164929
Uniprot IDs		P54709	Q8WXS3
PDB IDs
Enriched GO Terms of Interacting Partners?
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