ATP1B3 and SMAGP

Data Source:
BioGRID (two hybrid)

		ATP1B3	SMAGP
Description		ATPase Na+/K+ transporting subunit beta 3	small cell adhesion glycoprotein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome	Nucleoplasm Plasma Membrane Integral Component Of Membrane Cell Junction Cytoplasmic Vesicle Membrane
	Molecular Function	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding	Protein Binding
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 32888494 27863252 28957414) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)	Mean platelet volume ( 32888494)
Interacting Genes		13 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4	39 interacting genes: APH1A AQP6 ARL13B ATP1B3 C2orf74 CD53 EBP ERGIC3 FFAR2 GPX8 IL3RA JAGN1 MFSD14B OPRD1 OPRM1 PIGP PLPP6 PLPPR2 REEP4 RNASEK SERINC2 SGTA SLC10A6 SLC16A7 SPACA1 SUSD3 TLCD4 TMEM106C TMEM14B TMEM205 TMEM234 TMEM31 TMEM45B TMEM51 TMEM80 TMPPE TMX2 UPK2 YWHAE
Entrez ID		483	57228
HPRD ID		03521	14256
Ensembl ID		ENSG00000069849	ENSG00000170545
Uniprot IDs		P54709	Q0VAQ4
PDB IDs
Enriched GO Terms of Interacting Partners?
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