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LRRC18 and FRS3
Data Source:
BioGRID
(two hybrid)
LRRC18
FRS3
Description
leucine rich repeat containing 18
fibroblast growth factor receptor substrate 3
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Molecular Function
Protein Binding
Fibroblast Growth Factor Receptor Binding
Protein Binding
Identical Protein Binding
Biological Process
MAPK Cascade
Signal Transduction
Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
FRS-mediated FGFR3 signaling
FRS-mediated FGFR4 signaling
RAF/MAP kinase cascade
Activated NTRK2 signals through FRS2 and FRS3
Drugs
Diseases
GWAS
Subclinical atherosclerosis traits (other) (
17903303
)
Systemic lupus erythematosus (
19838193
)
Menarche (age at onset) (
25231870
)
Interacting Genes
4 interacting genes:
FRS3
KCTD17
MEOX2
ZBTB24
111 interacting genes:
ADAMTSL4
ANAPC11
ANKRD55
ATP23
BLZF1
BMPR2
C11orf1
C11orf45
C19orf54
C22orf39
CATSPER1
CBY2
CCDC33
CCN3
CDPF1
COL8A1
COPS3
CREB5
CYSRT1
DCDC2B
DDX5
DMRT3
DPEP2NB
ECM1
ESM1
FGFR1
GATA1
GPRIN2
GRB14
GRB2
HOXA1
HOXD12
ID2
ID3
IKZF3
INCA1
ISY1-RAB43
KARS1
KATNBL1
KIAA0408
KPRP
KRT31
KRT33B
KRT34
KRT35
KRT76
KRTAP1-1
KRTAP10-8
KRTAP11-1
KRTAP3-1
KRTAP3-2
KRTAP6-2
LINGO1
LRRC18
MAPK1
MATK
MBD3L1
MIIP
NADSYN1
NBPF19
NOTCH2NLA
NTRK1
NTRK2
NUMB
PCSK5
PDLIM7
PIH1D2
PLB1
PLLP
PLSCR1
POF1B
PPP1R32
PRDM6
PRKCI
PTPN11
RFX6
RIMBP3C
RND1
SCNM1
SH2B1
SLAIN1
SLC22A18AS
SOCS6
SPATA12
SPRY2
STH
STK16
TCF4
TCP10L
TGM7
TLE5
TNS1
TRAF4
TRIP6
TSC1
TSGA10IP
TSPAN4
UNKL
VASP
VGLL3
WDR83
WWOX
YPEL3
ZMIZ2
ZNF124
ZNF417
ZNF438
ZNF446
ZNF552
ZNF69
ZSCAN30
Entrez ID
474354
10817
HPRD ID
17450
06373
Ensembl ID
ENSG00000165383
ENSG00000137218
Uniprot IDs
Q8N456
A0A140VJJ7
O43559
PDB IDs
2KUP
2KUQ
2YS5
2YT2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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