CEACAM6 and GPANK1

Data Source:
BioGRID (two hybrid)

		CEACAM6	GPANK1
Description		CEA cell adhesion molecule 6	G-patch domain and ankyrin repeats 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	Nucleic Acid Binding Protein Binding
	Biological Process	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Neutrophil Degranulation Leukocyte Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation
Drugs
Diseases
GWAS		Serum carcinoembryonic antigen levels ( 31666285)	Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Febrile seizures (MMR vaccine-related) ( 25344690) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)
Interacting Genes		32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76	89 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 BHLHB9 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FAM166B FTO GOLGA2 GOLGA6L9 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1
Entrez ID		4680	7918
HPRD ID		01233	00810
Ensembl ID		ENSG00000086548	ENSG00000204438
Uniprot IDs		P40199	A0A024RCU2 B2RA66 O95872
PDB IDs		4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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