CEACAM6 and ASPG

Data Source:
BioGRID (two hybrid)

		CEACAM6	ASPG
Description		CEA cell adhesion molecule 6	asparaginase
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Apical Plasma Membrane Anchored Component Of Membrane Azurophil Granule Membrane	Cytosol
	Molecular Function	Protein Binding Identical Protein Binding Protein Heterodimerization Activity	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Asparaginase Activity Lysophospholipase Activity Protein Binding Transferase Activity, Transferring Acyl Groups Other Than Amino-acyl Groups Phosphatidyl Phospholipase B Activity
	Biological Process	Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Neutrophil Degranulation Leukocyte Migration Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Negative Regulation Of Anoikis	Cellular Amino Acid Biosynthetic Process Lipid Catabolic Process
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall Neutrophil degranulation	Aspartate and asparagine metabolism
Drugs			Procaine
Diseases
GWAS		Serum carcinoembryonic antigen levels ( 31666285)	Blood metabolite levels ( 24816252) Body mass index ( 26426971) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Plasma free asparagine levels ( 30659259) Refractive error ( 32231278) Schizophrenia ( 29483656) Serum metabolite concentrations in chronic kidney disease ( 29545352)
Interacting Genes		32 interacting genes: APP ASPG CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8 CIB1 CSTF2 EXOC3L1 FOXH1 GCM2 GPANK1 HGS HPCAL4 KANK2 MSS51 MYOZ1 PITX1 POM121 QRICH1 RHOXF2 SHC3 SMARCD1 TLX3 TNXB UBQLN2 VENTX VEZF1 WWOX ZMYND19 ZNF76	12 interacting genes: C20orf85 CEACAM6 DMRT3 GSDMD MYOZ3 RTP5 SGK1 SHC3 TEKT3 TMEM115 USP2 VPS25
Entrez ID		4680	374569
HPRD ID		01233	19180
Ensembl ID		ENSG00000086548	ENSG00000166183
Uniprot IDs		P40199	Q86U10
PDB IDs		4WHC 4WTZ 4Y8A 4YIQ
Enriched GO Terms of Interacting Partners?
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