GPANK1 and SPATA2

Data Source:
BioGRID (two hybrid)

		GPANK1	SPATA2
Description		G-patch domain and ankyrin repeats 1	spermatogenesis associated 2
Image		No pdb structure
GO Annotations	Cellular Component		Fibrillar Center Nucleoplasm Cytoplasm
	Molecular Function	Nucleic Acid Binding Protein Binding	Protein Binding Signaling Receptor Complex Adaptor Activity Protein-containing Complex Binding Ubiquitin-specific Protease Binding
	Biological Process		Spermatogenesis Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Inflammatory Response Regulation Of Necroptotic Process Necroptotic Process Protein K63-linked Deubiquitination Seminiferous Tubule Development Protein Linear Deubiquitination
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Febrile seizures (MMR vaccine-related) ( 25344690) Inflammatory bowel disease ( 28067908) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Coronary artery disease ( 29212778) Gut microbiota (beta diversity) ( 27723756) Psoriasis ( 20953189 25574825 18364390)
Interacting Genes		89 interacting genes: ABI2 AKAP8L ANAPC11 AP1B1 AP2B1 APP BAG4 BHLHB9 C1QTNF2 CADPS CCDC184 CCDC33 CCDC85B CEACAM6 CYSRT1 DDI1 DHX15 DISC1 ECM1 EFS FAM166B FTO GOLGA2 GOLGA6L9 GRB2 HNRNPH1 HOMEZ HSF2BP HYI INKA1 INSC KANK2 KATNBL1 KCTD9 KRT75 KRTAP10-8 KRTAP12-2 KRTAP13-3 KRTAP19-5 KRTAP19-6 LDOC1 LIG4 LZTS2 MAGED1 MAGOHB MDFI MEOX1 MEOX2 METTL27 METTL6 MID2 MORN3 NADSYN1 NFKBID NR1H3 NUTM1 OIP5 PATZ1 PAX6 PBX4 PFDN5 PLAAT1 PNMA1 PPARA PPP4C PRDM6 PTH1R RIMBP3C RTL8C SORBS3 SPATA2 STMN3 STX5 TEPSIN TFCP2 TLE5 TRAF2 TRAPPC2L TRIM23 TRIM27 TSC1 TTC19 TTC23 VBP1 ZBTB16 ZBTB8OS ZMAT5 ZNF688 ZRANB1	22 interacting genes: ANKRD11 APP ATP6V1H C2CD6 CCDC102B CEP72 DUT EFHC1 GOLGA2 GPANK1 KAT5 KIFC3 LENG1 MAD1L1 OTULIN PTPN6 RNF31 TBC1D22B TNIP1 TRAF2 TRIM27 ZNF835
Entrez ID		7918	9825
HPRD ID		00810	09636
Ensembl ID		ENSG00000204438	ENSG00000158480
Uniprot IDs		A0A024RCU2 B2RA66 O95872	A8K0S9 B4DID4 Q9UM82
PDB IDs			5LJM 5LJN
Enriched GO Terms of Interacting Partners?
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