RAMP3 and SLC31A2

Data Source:
BioGRID (pull down)

		RAMP3	SLC31A2
Description		receptor activity modifying protein 3	solute carrier family 31 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex	Late Endosome Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome
	Molecular Function	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity	Copper Ion Transmembrane Transporter Activity Protein Binding
	Biological Process	Angiogenesis Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Transmembrane Transport Regulation Of Copper Ion Transmembrane Transport
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pramlintide
Diseases
GWAS		Hepatic lipid content in extreme obesity ( 25246029)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494)
Interacting Genes		15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1	9 interacting genes: BNIP3 F2RL1 GPR35 HTR2B OPRL1 RAMP1 RAMP2 RAMP3 VKORC1
Entrez ID		10268	1318
HPRD ID		05517	04365
Ensembl ID		ENSG00000122679	ENSG00000136867
Uniprot IDs		A4D2L1 O60896	O15432 Q53X94
PDB IDs		6UUS 6UVA
Enriched GO Terms of Interacting Partners?
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