GET3 and GPX7

Data Source:
BioGRID (two hybrid)

		GET3	GPX7
Description		guided entry of tail-anchored proteins factor 3, ATPase	glutathione peroxidase 7
Image
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Detoxification of Reactive Oxygen Species
Drugs		ATP	Glutathione Glutathione Glutathione disulfide
Diseases
GWAS			Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	13 interacting genes: ASPH CEP70 CPEB2 CPNE7 ERO1A GET3 NCALD NTAQ1 SGTA SGTB TCF25 UBQLN2 UBQLN4
Entrez ID		439	2882
HPRD ID		03555	13606
Ensembl ID		ENSG00000198356	ENSG00000116157
Uniprot IDs		O43681	Q96SL4
PDB IDs		6SO5	2P31
Enriched GO Terms of Interacting Partners?
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