GET3 and TMEM154

Data Source:
BioGRID (two hybrid)

		GET3	TMEM154
Description		guided entry of tail-anchored proteins factor 3, ATPase	transmembrane protein 154
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding	Protein Binding
	Biological Process	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		ATP
Diseases
GWAS			Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Hip circumference ( 28552196) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Type 2 diabetes ( 24509480 30054458 29358691 30297969 32499647 30718926 28869590)
Interacting Genes		41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3	11 interacting genes: CLCA4 CTSA CYB561D2 FUNDC2 FXYD6 GET3 GYPA MIP SGTA SLC35A4 SMIM1
Entrez ID		439	201799
HPRD ID		03555	08719
Ensembl ID		ENSG00000198356	ENSG00000170006
Uniprot IDs		O43681	D6R923 Q6P9G4
PDB IDs		6SO5
Enriched GO Terms of Interacting Partners?
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