GPX7 and GET3

Data Source:
BioGRID (two hybrid)

		GPX7	GET3
Description		glutathione peroxidase 7	guided entry of tail-anchored proteins factor 3, ATPase
Image
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Catalase Activity Peroxidase Activity Glutathione Peroxidase Activity Protein Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Cellular Response To Oxidative Stress Cellular Oxidant Detoxification	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Detoxification of Reactive Oxygen Species	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Glutathione Glutathione Glutathione disulfide	ATP
Diseases
GWAS		Blood protein levels ( 29875488) Joint mobility (Beighton score) ( 27182965)
Interacting Genes		13 interacting genes: ASPH CEP70 CPEB2 CPNE7 ERO1A GET3 NCALD NTAQ1 SGTA SGTB TCF25 UBQLN2 UBQLN4	41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3
Entrez ID		2882	439
HPRD ID		13606	03555
Ensembl ID		ENSG00000116157	ENSG00000198356
Uniprot IDs		Q96SL4	O43681
PDB IDs		2P31	6SO5
Enriched GO Terms of Interacting Partners?
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