TMEM154 and GET3

Data Source:
BioGRID (two hybrid)

		TMEM154	GET3
Description		transmembrane protein 154	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process		Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS		Gut microbiota relative abundance (unclassified genus belonging to family Lachnospiraceae) ( 33208821) Hip circumference ( 28552196) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Type 2 diabetes ( 24509480 30054458 29358691 30297969 32499647 30718926 28869590)
Interacting Genes		11 interacting genes: CLCA4 CTSA CYB561D2 FUNDC2 FXYD6 GET3 GYPA MIP SGTA SLC35A4 SMIM1	41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3
Entrez ID		201799	439
HPRD ID		08719	03555
Ensembl ID		ENSG00000170006	ENSG00000198356
Uniprot IDs		D6R923 Q6P9G4	O43681
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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