MAGEA6 and ATPAF2

Data Source:
BioGRID (two hybrid)

		MAGEA6	ATPAF2
Description		MAGE family member A6	ATP synthase mitochondrial F1 complex assembly factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component	Mitochondrion Cytosol Nuclear Speck
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	Biological_process	Proton-transporting ATP Synthase Complex Assembly
Pathways
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Schizophrenia ( 28991256 25056061 29483656)
Interacting Genes		74 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FAM214A FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76	73 interacting genes: AKAP8L APP ATP5F1A ATP5F1B BEGAIN C11orf1 CDC14A CDK2AP1 CEP57 CFAP206 CRTC2 CTIF CYSRT1 DDIT3 DLGAP4 EBF1 EBF3 EIF4G1 EWSR1 FAM166B FCHSD2 FNTB GOLGA6L9 IKZF3 INCA1 KRT34 KRT40 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-2 KRTAP6-3 LGALS9B LNX1 LRRFIP2 LURAP1L LZTS2 MAGEA6 MEDAG MIF4GD NME4 PAK5 PKP4 POLR2J3 POLR3F POLR3H PPP1R16B PPP1R32 PRDM14 PRDM6 RAD54B RBM48 RCN1 REL RPH3AL RPIA SORBS2 SPATC1L SPG21 TCHP TFIP11 TP53BP2 TRIM23 TRIM27 UBAP2 VWC2 WASHC1 ZFP90 ZNF19 ZNF23 ZNF35 ZNF426 ZNF655
Entrez ID		4105	91647
HPRD ID		02168	10599
Ensembl ID		ENSG00000197172	ENSG00000171953
Uniprot IDs		P43360	Q8N5M1
PDB IDs
Enriched GO Terms of Interacting Partners?
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