EXOC5 and MAGEA3

Data Source:
BioGRID (two hybrid)

		EXOC5	MAGEA3
Description		exocyst complex component 5	MAGE family member A3
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Endoplasmic Reticulum
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Caspase Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport	Negative Regulation Of Protein Processing Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)
Interacting Genes		43 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	16 interacting genes: ACOT7 BCL7B C17orf49 CINP DNM1L ENOX2 EXOC5 HLA-DRB1 HTT IQSEC1 KIF27 LSM2 PCYT1A RUSC1 S100A9 STAMBPL1
Entrez ID		10640	4102
HPRD ID		07258	02166
Ensembl ID		ENSG00000070367	ENSG00000221867
Uniprot IDs		O00471	P43357
PDB IDs			1QEW 4V0P 5BRZ
Enriched GO Terms of Interacting Partners?
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