EXOC5 and THOC1

Data Source:
BioGRID (two hybrid)

		EXOC5	THOC1
Description		exocyst complex component 5	THO complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck
	Molecular Function	Protein Binding Small GTPase Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)	Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799) Triglyceride levels ( 32203549)
Interacting Genes		43 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 HDDC3 HGS ICA1 IFT57 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	26 interacting genes: AGR2 AKAP9 BHLHB9 CTAG1A CTAG1B DHX8 EXOC5 FRA10AC1 IK MAGEB4 MOAP1 MTNR1B NEDD4 PAX6 PPP1R12C RABGEF1 RB1 REL SAP30BP SF3B2 TADA2A TRIM27 TRIM54 USHBP1 WDR77 ZMYND12
Entrez ID		10640	9984
HPRD ID		07258	09498
Ensembl ID		ENSG00000070367	ENSG00000079134
Uniprot IDs		O00471	Q96FV9
PDB IDs			1WXP
Enriched GO Terms of Interacting Partners?
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