PCGF6 and SS18L1

Data Source:
BioGRID (two hybrid)

		PCGF6	SS18L1
Description		polycomb group ring finger 6	SS18L1 subunit of BAF chromatin remodeling complex
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Kinetochore Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytosol Nuclear Body NBAF Complex
	Molecular Function	Protein Binding Metal Ion Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Histone H2A-K119 Monoubiquitination Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Chromatin Organization Dendrite Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Dendrite Morphogenesis
Pathways		Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		26 interacting genes: BMI1 CBX6 CBX7 CDK7 E2F6 EIF2B2 H3-4 KDM5D MAGEA1 MAGEC2 MAGEE2 MAGEL2 PEX10 PNMA1 RAD18 RING1 RNF2 SS18L1 TRIM14 TRIM55 TRIM63 TULP3 UBE2D3 UBE2U USP2 USP21	43 interacting genes: AATF ANKRD22 ATF3 ATN1 BAG4 BICRAL BRD1 C1orf94 CEP55 CREBBP CSTF2 DGCR6 ELF5 EP300 FAM168A GATAD1 HDAC2 HDAC4 HGS LGALS3 MAPK1IP1L MED30 MIA2 NAF1 NR1H3 PAX8 PCGF6 RFX6 RLIM SF3B4 SMAD1 SMAD3 SMARCA4 SNRPB SNRPC SSBP3 STAT3 TAF9B TCF7 TNK1 USP54 ZMIZ2 ZMYND19
Entrez ID		84108	26039
HPRD ID		07427	09398
Ensembl ID		ENSG00000156374	ENSG00000184402
Uniprot IDs		Q9BYE7	B4DSR7 O75177
PDB IDs		2DJB
Enriched GO Terms of Interacting Partners?
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