Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SMAD1 and CHMP3
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
SMAD1
CHMP3
Description
SMAD family member 1
charged multivesicular body protein 3
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nuclear Inner Membrane
Nucleoplasm
Cytoplasm
Cytosol
Integral Component Of Membrane
Protein-containing Complex
SMAD Protein Complex
Heteromeric SMAD Protein Complex
ESCRT III Complex
Late Endosome
Multivesicular Body
Cytosol
Plasma Membrane
Cytoplasmic Vesicle
Late Endosome Membrane
Extracellular Exosome
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
DEAD/H-box RNA Helicase Binding
Protein Kinase Binding
Identical Protein Binding
Metal Ion Binding
Co-SMAD Binding
I-SMAD Binding
Primary MiRNA Binding
Protein Binding
Phosphatidylcholine Binding
Ubiquitin-specific Protease Binding
Biological Process
MAPK Cascade
Ureteric Bud Development
Mesodermal Cell Fate Commitment
Osteoblast Fate Commitment
Regulation Of Transcription By RNA Polymerase II
Protein Phosphorylation
Inflammatory Response
Signal Transduction
Transforming Growth Factor Beta Receptor Signaling Pathway
SMAD Protein Complex Assembly
Gamete Generation
Negative Regulation Of Cell Population Proliferation
Anatomical Structure Morphogenesis
Embryonic Pattern Specification
Positive Regulation Of Gene Expression
Protein Deubiquitination
Cell Differentiation
BMP Signaling Pathway
Midbrain Development
Hindbrain Development
Primary MiRNA Processing
Homeostatic Process
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Cartilage Development
Cardiac Muscle Cell Proliferation
Bone Development
SMAD Protein Signal Transduction
Positive Regulation Of Cartilage Development
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II
Positive Regulation Of Sprouting Angiogenesis
Apoptotic Process
Nucleus Organization
Mitotic Metaphase Plate Congression
Regulation Of Centrosome Duplication
Protein Transport
Endosomal Transport
Macroautophagy
Viral Life Cycle
Endosome Transport Via Multivesicular Body Sorting Pathway
Multivesicular Body Assembly
Viral Budding Via Host ESCRT Complex
Late Endosome To Vacuole Transport
Regulation Of Viral Process
Protein Polymerization
Multivesicular Body-lysosome Fusion
Midbody Abscission
Multivesicular Body Sorting Pathway
Autophagosome Maturation
Regulation Of Mitotic Spindle Assembly
Negative Regulation Of Viral Release From Host Cell
Positive Regulation Of Viral Release From Host Cell
Regulation Of Exosomal Secretion
Regulation Of Early Endosome To Late Endosome Transport
Pathways
Signaling by BMP
Ub-specific processing proteases
RUNX2 regulates bone development
Budding and maturation of HIV virion
Macroautophagy
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events
Late endosomal microautophagy
Sealing of the nuclear envelope (NE) by ESCRT-III
Translation of Replicase and Assembly of the Replication Transcription Complex
Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Hemoglobin (
32888494
)
Lung function (FEV1) (
30061609
)
Malaria (
31844061
)
Midgestational cytokine/chemokine levels (maternal genetic effect) (
30134952
)
Panic disorder (
31712720
)
Red cell distribution width (
32888494
)
Response to cognitive-behavioural therapy in anxiety disorder (
26989097
)
Adult body size (
32376654
)
Glomerular filtration rate in chronic kidney disease (
26420894
)
Nicotine dependence symptom count (
25555482
)
Interacting Genes
160 interacting genes:
ACVR1
ACVRL1
AKR1B1
ANKRD27
AP2A2
APC
APP
AR
ARHGEF6
ARL4D
AXIN2
BMPR1A
BTBD2
BTG2
BUB1
CAMSAP1
CCND1
CDK7
CDK9
CHMP3
CILK1
COL4A1
CTNNA1
DACH1
DLC1
DNMT3L
DVL1
ECSIT
EIF2AK4
ELP3
EP300
EPN2
ERBB2
ERBIN
EWSR1
FBXL12
FBXO30
FBXW7
FHL5
FOXG1
FRZB
GDF6
GLI3
GMEB1
GSC
HBP1
HIPK2
HOXA13
HOXA5
HOXC8
HOXD13
ING2
INPP4A
IRF2BP1
KAT2B
KMT2D
LEF1
LEMD3
LMNA
MAP2K3
MAPK1
MAST4
MBD1
MECOM
MED6
MEN1
MGA
MLH1
MLH3
MRTFB
MSH2
MUTYH
NAT9
NEDD4
NEDD9
NEUROG1
NKX3-2
NOTCH2
NRAS
OAZ1
OAZ3
PAK1
PARD3
PDGFRL
PIAS1
PIAS4
PIGQ
PLEKHB1
PREB
PSMB4
PSMD1
PSMD11
PTPN12
PUM1
RAB2B
RAB30
RAB34
RAB38
RAB3B
RAB6B
RAC2
RAN
RAP2A
RASD2
RASL12
RFX1
RHEBL1
RHOG
RPS27A
SF3B1
SKI
SKIL
SMAD2
SMAD3
SMAD4
SMAD5
SMAD6
SMARCE1
SMURF1
SMURF2
SNIP1
SNRNP70
SOX5
SQSTM1
SS18L1
STARD13
STK11
STUB1
SUV39H1
TCF20
TET2
TGFBR1
TLR2
TNNT1
TOB1
TRIP6
TTF1
TTF2
UBA52
UBC
UBE2Z
UBXN1
USP45
VEPH1
WDR77
XPC
XPO1
YAP1
YY1
ZBTB44
ZDHHC3
ZEB2
ZNF251
ZNF423
ZNF510
ZNF512B
ZNF521
ZNF76
ZNF8
ZSCAN4
13 interacting genes:
APP
CHMP2A
CHMP2B
CHMP4A
CHMP4B
FBXO7
IGFBP7
RAB11A
SMAD1
SMAD5
STAMBP
TNPO3
VAV2
Entrez ID
4086
51652
HPRD ID
03356
15650
Ensembl ID
ENSG00000170365
ENSG00000115561
Uniprot IDs
Q15797
Q9Y3E7
PDB IDs
1KHU
2LAW
2LAX
2LAY
2LAZ
2LB0
2LB1
3Q47
3Q4A
5ZOK
2GD5
2XZE
3FRT
3FRV
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?