MAD2L1 and NDC80

  • Data Source:
  • HPRD (in vivo)

MAD2L1

NDC80

Description mitotic arrest deficient 2 like 1 NDC80 kinetochore complex component
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 32469254 28714974 33020668)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • F-cell distribution in sickle cell anaemia ( 21326311)
  • HIV-1 viral setpoint ( 22174851)
  • Loneliness (multivariate analysis) ( 27629369)
  • Refractive error ( 32231278)
  • Metabolite levels ( 23823483)
  • Response to cognitive-behavioural therapy in major depressive disorder ( 31123309)
Interacting Genes 26 interacting genes: ADAM17 ANAPC2 ANAPC4 APP CCNA2 CDC16 CDC20 CDC27 CSF2RB DEPDC5 EPM2AIP1 ESR2 H3C1 INSR KEAP1 MAD1L1 MAD2L1BP MAD2L2 MBL2 NDC80 RABAC1 REV3L SDCBP TRIP13 TSC22D4 UBD 64 interacting genes: AMOTL2 ATF4 ATP5PO ATP6V1D AURKA AURKB BLOC1S6 CAGE1 CALCOCO1 CCDC136 CCHCR1 CCNH CCNK CENPH CEP63 CKAP5 EPS15L1 EXOC8 FAM9C GOLGA2 HAUS1 HGS HIP1R IFT20 INPP1 KIFC3 KLC3 KLHL12 KRT27 KRT6B KRT75 LNX1 MAD1L1 MAD2L1 MFAP1 MIS12 NDE1 NDEL1 NEK2 NUF2 PCM1 PFDN1 PPP1R13B PSMC2 RB1 RUFY4 SFR1 SGF29 SKA1 SMC1A SPC25 STX11 TFIP11 THOC7 TNIP1 TOM1L1 TP53BP2 TXLNA USHBP1 VPS52 WASHC1 WASHC3 ZNF655 ZWINT
Entrez ID 4085 10403
HPRD ID 03274 06277
Ensembl ID ENSG00000164109 ENSG00000080986
Uniprot IDs Q13257 A8K031 O14777
PDB IDs 1DUJ 1GO4 1KLQ 1S2H 2QYF 2V64 2VFX 3GMH 5KHU 5LCW 6F0X 6TLJ 2IGP 2VE7 3IZ0
Enriched GO Terms of Interacting Partners?
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