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NDC80 and CAGE1
Data Source:
BioGRID
(two hybrid)
NDC80
CAGE1
Description
NDC80 kinetochore complex component
cancer antigen 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Centromeric Region
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome Kinetochore
Condensed Nuclear Chromosome Outer Kinetochore
Nucleus
Nucleoplasm
Centrosome
Cytosol
Membrane
Ndc80 Complex
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Biological Process
Mitotic Sister Chromatid Segregation
Establishment Of Mitotic Spindle Orientation
Mitotic Cell Cycle
Mitotic Spindle Organization
Chromosome Segregation
Attachment Of Spindle Microtubules To Kinetochore
Centrosome Duplication
Cell Division
Metaphase Plate Congression
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Kinetochore Organization
Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Positive Regulation Of Protein Localization To Kinetochore
Pathways
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase
EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Response to cognitive-behavioural therapy in major depressive disorder (
31123309
)
Ewing sarcoma (
30093639
)
Pursuit maintenance gain (
29064472
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Interacting Genes
64 interacting genes:
AMOTL2
ATF4
ATP5PO
ATP6V1D
AURKA
AURKB
BLOC1S6
CAGE1
CALCOCO1
CCDC136
CCHCR1
CCNH
CCNK
CENPH
CEP63
CKAP5
EPS15L1
EXOC8
FAM9C
GOLGA2
HAUS1
HGS
HIP1R
IFT20
INPP1
KIFC3
KLC3
KLHL12
KRT27
KRT6B
KRT75
LNX1
MAD1L1
MAD2L1
MFAP1
MIS12
NDE1
NDEL1
NEK2
NUF2
PCM1
PFDN1
PPP1R13B
PSMC2
RB1
RUFY4
SFR1
SGF29
SKA1
SMC1A
SPC25
STX11
TFIP11
THOC7
TNIP1
TOM1L1
TP53BP2
TXLNA
USHBP1
VPS52
WASHC1
WASHC3
ZNF655
ZWINT
13 interacting genes:
BFSP2
FCRL5
HAUS1
KDM1A
MPPED2
MRFAP1L1
NDC80
NECAB2
PPFIA1
TBC1D23
TPM1
TSG101
TXLNB
Entrez ID
10403
285782
HPRD ID
06277
10511
Ensembl ID
ENSG00000080986
ENSG00000164304
Uniprot IDs
A8K031
O14777
Q8TC20
PDB IDs
2IGP
2VE7
3IZ0
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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