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MIR16-1 and APOBEC3B
Data Source:
BioGRID
(unspecified method)
MIR16-1
APOBEC3B
Description
microRNA 16-1
apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
P-body
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
Cytidine Deaminase Activity
Protein Binding
Zinc Ion Binding
Deoxycytidine Deaminase Activity
Biological Process
Branching Involved In Blood Vessel Morphogenesis
Negative Regulation Of Endothelial Cell Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Placenta Blood Vessel Development
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of Endothelial Cell Chemotaxis To Vascular Endothelial Growth Factor
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Cytidine Deamination
Negative Regulation Of Transposition
Cytidine To Uridine Editing
Innate Immune Response
Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate
Defense Response To Virus
DNA Cytosine Deamination
DNA Demethylation
Pathways
mRNA Editing: C to U Conversion
Formation of the Editosome
Drugs
Diseases
GWAS
Asthma exacerbations in inhaled corticosteroid treatment (
30697902
)
Breast cancer (
29059683
)
Response to methotrexate in juvenile idiopathic arthritis (
24709693
)
Interacting Genes
71 interacting genes:
APOBEC3B
C1QBP
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
RARS1
RBFOX2
RBM14
RBM47
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
61 interacting genes:
AGR2
BNIP2
MIR1-1
MIR1-2
MIR106A
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A2
MIR19A
MIR19B1
MIR200A
MIR200B
MIR205
MIR20A
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-2
MIR9-3
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MSL2
Entrez ID
406950
9582
HPRD ID
06169
Ensembl ID
ENSG00000208006
ENSG00000179750
Uniprot IDs
Q9UH17
PDB IDs
2NBQ
5CQD
5CQH
5CQI
5CQK
5SXG
5SXH
5TD5
5TKM
6NFK
6NFL
6NFM
Enriched GO Terms of Interacting Partners
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