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MIR16-1 and DDX3X
Data Source:
BioGRID
(unspecified method)
MIR16-1
DDX3X
Description
microRNA 16-1
DEAD-box helicase 3 X-linked
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Plasma Membrane
Cytoplasmic Stress Granule
Cytosolic Small Ribosomal Subunit
Lamellipodium
Cell Leading Edge
Secretory Granule Lumen
P Granule
Extracellular Exosome
NLRP3 Inflammasome Complex
Ficolin-1-rich Granule Lumen
Molecular Function
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
DNA Binding
DNA Helicase Activity
RNA Binding
RNA Helicase Activity
MRNA Binding
GTPase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Poly(A) Binding
Eukaryotic Initiation Factor 4E Binding
ATPase Activity
Nucleoside-triphosphatase Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
RNA Stem-loop Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
CTPase Activity
Protein Serine/threonine Kinase Activator Activity
Cadherin Binding
MRNA 5'-UTR Binding
Biological Process
Branching Involved In Blood Vessel Morphogenesis
Negative Regulation Of Endothelial Cell Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Placenta Blood Vessel Development
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of Endothelial Cell Chemotaxis To Vascular Endothelial Growth Factor
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Translational Initiation
Chromosome Segregation
Gamete Generation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Response To Virus
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Viral Process
Wnt Signaling Pathway
Negative Regulation Of Translation
Cell Differentiation
Positive Regulation Of Cell Growth
Negative Regulation Of Cell Growth
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Autophosphorylation
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Stress Granule Assembly
Positive Regulation Of Toll-like Receptor 7 Signaling Pathway
Positive Regulation Of Toll-like Receptor 8 Signaling Pathway
Intracellular Signal Transduction
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Mature Ribosome Assembly
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Neutrophil Degranulation
Positive Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Translation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Translational Initiation
Lipid Homeostasis
Cellular Response To Arsenic-containing Substance
Cellular Response To Osmotic Stress
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Cellular Response To Virus
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein Acetylation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein K63-linked Ubiquitination
Protein Localization To Cytoplasmic Stress Granule
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Neutrophil degranulation
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Interacting Genes
71 interacting genes:
APOBEC3B
C1QBP
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
RARS1
RBFOX2
RBM14
RBM47
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
92 interacting genes:
APBB1
CSNK2A1
DUX4
ESR1
HNF4A
IKBKE
IL7R
LINC01554
MAVS
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NFKB2
NUP62
PIN1
SREK1
SRPK2
SUMO2
WBP4
XPO1
YWHAQ
ZNF512B
Entrez ID
406950
1654
HPRD ID
02154
Ensembl ID
ENSG00000208006
ENSG00000215301
Uniprot IDs
A0A2R8Y7T2
A0A2R8YFS5
O00571
PDB IDs
2I4I
2JGN
3JRV
4O2C
4O2E
4O2F
4PX9
4PXA
5E7I
5E7J
5E7M
6CZ5
6O5F
Enriched GO Terms of Interacting Partners
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