MIR143 and APOBEC3B

Data Source:
BioGRID (unspecified method)

		MIR143	APOBEC3B
Description		microRNA 143	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome	P-body Nucleus Nucleoplasm Cytoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Regulation Of Smooth Muscle Contraction Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Activation Of Protein Kinase B Activity Gene Silencing By MiRNA Angiotensin-activated Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Positive Regulation Of Angiogenesis Negative Regulation Of Glucose Import Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Kinase B Signaling Aorta Smooth Muscle Tissue Morphogenesis Regulation Of Phenotypic Switching Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Pulmonary Blood Vessel Remodeling	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS			Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		79 interacting genes: ADARB1 APOBEC3B C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H10	61 interacting genes: AGR2 BNIP2 MIR1-1 MIR1-2 MIR106A MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR205 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR9-3 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MSL2
Entrez ID		406935	9582
HPRD ID			06169
Ensembl ID		ENSG00000284182	ENSG00000179750
Uniprot IDs			Q9UH17
PDB IDs			2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM 6NFK 6NFL 6NFM
Enriched GO Terms of Interacting Partners?
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