MIR143 and DDX23

Data Source:
BioGRID (unspecified method)

		MIR143	DDX23
Description		microRNA 143	DEAD-box helicase 23
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome	Chromatin Nucleus Nucleoplasm U5 SnRNP Nucleolus U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of Smooth Muscle Contraction Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Activation Of Protein Kinase B Activity Gene Silencing By MiRNA Angiotensin-activated Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Establishment Or Maintenance Of Cell Type Involved In Phenotypic Switching Positive Regulation Of Angiogenesis Negative Regulation Of Glucose Import Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Kinase B Signaling Aorta Smooth Muscle Tissue Morphogenesis Regulation Of Phenotypic Switching Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Pulmonary Blood Vessel Remodeling	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing R-loop Disassembly
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Interacting Genes		79 interacting genes: ADARB1 APOBEC3B C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 FAM98A FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SFPQ SPOUT1 STRBP SUGP2 SYNCRIP TAF15 TRA2A TRA2B TUT4 U2SURP UPF1 UTP20 YBX1 YBX3 ZC3H10	25 interacting genes: ERG MIR106B MIR128-1 MIR138-2 MIR141 MIR143 MIR19B2 MIR200B MIR200C MIR214 MIR25 MIR363 MIR429 MIR7-1 MIR7-2 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7G MIRLET7I PCM1 TERF1 TERF2IP WBP4
Entrez ID		406935	9416
HPRD ID			09908
Ensembl ID		ENSG00000284182	ENSG00000174243
Uniprot IDs			A0A024R0Z3 B3KY11 Q9BUQ8
PDB IDs			3JCR 4NHO 6AH0 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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