MIRLET7G and CCAR1

Data Source:
BioGRID (unspecified method)

		MIRLET7G	CCAR1
Description		microRNA let-7g	cell division cycle and apoptosis regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Nucleus Nuclear Envelope Lumen Nucleoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	Negative Regulation Of Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing By MiRNA Positive Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Glucose Stimulus Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell	MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Positive Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Schizophrenia ( 23974872)	Cannabis dependence symptom count ( 27028160)
Interacting Genes		116 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PAXBP1 PDCD11 PLOD1 PLRG1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM10 RBM12B RBM14 RBM17 RBM4 RBM4B RBM5 RBM6 RBMS1 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SF3B5 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TUT4 TUT7 U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR	14 interacting genes: CASP10 CHERP DNAAF6 GOLGA2 HMGB1 HNRNPK MDM2 MIR106B MIRLET7G MTUS2 RBM10 RNF113A SFN U2AF2
Entrez ID		406890	55749
HPRD ID			10811
Ensembl ID		ENSG00000199150	ENSG00000060339
Uniprot IDs			Q8IX12
PDB IDs
Enriched GO Terms of Interacting Partners?
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