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MIRLET7G and PURA
Data Source:
BioGRID
(unspecified method)
MIRLET7G
PURA
Description
microRNA let-7g
purine rich element binding protein A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Chromosome, Telomeric Region
Nucleus
Dendrite Cytoplasm
Neuronal Cell Body
Postsynapse
Glutamatergic Synapse
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
Translation Repressor Activity, MRNA Regulatory Element Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Double-stranded Telomeric DNA Binding
Single-stranded DNA Binding
RNA Binding
Protein Binding
Transcription Factor Binding
Purine-rich Negative Regulatory Element Binding
SMAD Binding
Biological Process
Negative Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Silencing By MiRNA
Positive Regulation Of Angiogenesis
Negative Regulation Of Inflammatory Response
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Cellular Response To Glucose Stimulus
Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Negative Regulation Of Transcription By RNA Polymerase II
DNA Unwinding Involved In DNA Replication
DNA Replication Initiation
Regulation Of Transcription By RNA Polymerase II
Nervous System Development
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of Translation
Cell Differentiation
Lymphocyte Proliferation
Epithelial Cell Proliferation
Dendritic Transport Of Messenger Ribonucleoprotein Complex
Pathways
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Schizophrenia (
23974872
)
Body mass index (
26426971
)
Interacting Genes
116 interacting genes:
ADARB1
APOBEC3B
AQR
ATXN2L
C1QBP
CCAR1
CDC40
CDC5L
CELF1
CHERP
CPSF1
CRTAP
CSTF3
DARS1
DDX1
DDX21
DDX23
DDX3X
DDX3Y
DHX36
DHX37
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PAXBP1
PDCD11
PLOD1
PLRG1
PTBP1
PTCD3
PUF60
PUM1
PUM2
PURA
PURB
QARS1
RARS1
RBFOX2
RBM10
RBM12B
RBM14
RBM17
RBM4
RBM4B
RBM5
RBM6
RBMS1
RTCA
RTCB
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SF3B5
SFPQ
SPOUT1
STRBP
SUGP1
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
XAB2
YBX1
YBX2
YBX3
ZFR
57 interacting genes:
ADAP1
CCNT1
CDK5
E2F1
IL7R
MIR1-1
MIR106B
MIR122
MIR128-1
MIR128-2
MIR140
MIR143
MIR155
MIR15B
MIR16-2
MIR17
MIR18B
MIR199A1
MIR19A
MIR19B1
MIR19B2
MIR200C
MIR205
MIR20B
MIR21
MIR221
MIR222
MIR25
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR7-1
MIR7-2
MIR9-2
MIR92A2
MIR93
MIRLET7A1
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PTEN
PURB
RAF1
RB1
SP1
YBX1
Entrez ID
406890
5813
HPRD ID
02721
Ensembl ID
ENSG00000199150
ENSG00000185129
Uniprot IDs
Q00577
PDB IDs
Enriched GO Terms of Interacting Partners
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