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MIRLET7C and FUS
Data Source:
BioGRID
(unspecified method)
MIRLET7C
FUS
Description
microRNA let-7c
FUS RNA binding protein
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Extracellular Exosome
Extracellular Vesicle
Nucleus
Nucleoplasm
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
DNA Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
RNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-8 Production
Gene Silencing By MiRNA
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
MRNA Splicing, Via Spliceosome
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
RNA Splicing
Regulation Of RNA Splicing
Positive Regulation Of Transcription, DNA-templated
MRNA Stabilization
Protein Homooligomerization
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
mRNA Splicing - Major Pathway
Drugs
Diseases
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
Myxoid liposarcoma
GWAS
Bipolar disorder (
31043756
)
Bipolar I disorder (
31043756
)
HDL cholesterol levels (
32203549
)
Interacting Genes
96 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CHERP
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PLOD1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RBMS2
RTCA
RTCB
SART3
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
117 interacting genes:
ADAMTS9-AS2
AKT1
ARID1A
ATXN1L
CTNNB1
ESRRA
EWSR1
GRIN1
GRIN2D
IL7R
ILF3
KHDRBS3
MAX
MDH1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NKD2
POLR2A
PRMT1
PSMB7
PTBP1
RBMX
RELA
RXRA
SAFB2
SF1
SFPQ
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SPI1
SRRM1
SRSF10
SRSF2
SRSF4
SRSF9
SS18
SUV39H1
TARDBP
TDRD3
THRA
TNIP1
UBQLN2
WBP4
YBX1
ZMYM2
Entrez ID
406885
2521
HPRD ID
00660
Ensembl ID
ENSG00000199030
ENSG00000089280
Uniprot IDs
P35637
Q13344
Q6IBQ5
PDB IDs
2LA6
2LCW
4FDD
4FQ3
5W3N
5XRR
5XSG
5YVG
5YVH
5YVI
6BWZ
6BXV
6BZP
6G99
6GBM
6KJ1
6KJ2
6KJ3
6KJ4
6SNJ
6XFM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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