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FUS and MIR16-1
Data Source:
BioGRID
(unspecified method)
FUS
MIR16-1
Description
FUS RNA binding protein
microRNA 16-1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
DNA Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
RNA Binding
Protein Binding
Identical Protein Binding
Metal Ion Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
MRNA Splicing, Via Spliceosome
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
RNA Splicing
Regulation Of RNA Splicing
Positive Regulation Of Transcription, DNA-templated
MRNA Stabilization
Protein Homooligomerization
Positive Regulation Of Double-strand Break Repair Via Homologous Recombination
Branching Involved In Blood Vessel Morphogenesis
Negative Regulation Of Endothelial Cell Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Placenta Blood Vessel Development
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of Endothelial Cell Chemotaxis To Vascular Endothelial Growth Factor
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
mRNA Splicing - Major Pathway
Drugs
Diseases
Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
Myxoid liposarcoma
GWAS
Bipolar disorder (
31043756
)
Bipolar I disorder (
31043756
)
HDL cholesterol levels (
32203549
)
Interacting Genes
117 interacting genes:
ADAMTS9-AS2
AKT1
ARID1A
ATXN1L
CTNNB1
ESRRA
EWSR1
GRIN1
GRIN2D
IL7R
ILF3
KHDRBS3
MAX
MDH1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NKD2
POLR2A
PRMT1
PSMB7
PTBP1
RBMX
RELA
RXRA
SAFB2
SF1
SFPQ
SMARCB1
SMARCC1
SMARCC2
SMARCD1
SPI1
SRRM1
SRSF10
SRSF2
SRSF4
SRSF9
SS18
SUV39H1
TARDBP
TDRD3
THRA
TNIP1
UBQLN2
WBP4
YBX1
ZMYM2
71 interacting genes:
APOBEC3B
C1QBP
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
RARS1
RBFOX2
RBM14
RBM47
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
2521
406950
HPRD ID
00660
Ensembl ID
ENSG00000089280
ENSG00000208006
Uniprot IDs
P35637
Q13344
Q6IBQ5
PDB IDs
2LA6
2LCW
4FDD
4FQ3
5W3N
5XRR
5XSG
5YVG
5YVH
5YVI
6BWZ
6BXV
6BZP
6G99
6GBM
6KJ1
6KJ2
6KJ3
6KJ4
6SNJ
6XFM
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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