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MIRLET7C and AIMP1
Data Source:
BioGRID
(unspecified method)
MIRLET7C
AIMP1
Description
microRNA let-7c
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Extracellular Exosome
Extracellular Vesicle
Extracellular Space
Nucleus
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Cell Surface
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
TRNA Binding
Cytokine Activity
Protein Binding
Protein Homodimerization Activity
GTPase Binding
Biological Process
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-8 Production
Gene Silencing By MiRNA
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Angiogenesis
Negative Regulation Of Endothelial Cell Proliferation
TRNA Aminoacylation For Protein Translation
Apoptotic Process
Inflammatory Response
Signal Transduction
Cell-cell Signaling
Leukocyte Migration
Defense Response To Virus
Positive Regulation Of Glucagon Secretion
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Diseases
Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes
96 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CHERP
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PLOD1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RBMS2
RTCA
RTCB
SART3
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
50 interacting genes:
AIMP2
APP
ATP5F1A
HOMER1
IQGAP1
MAPK14
MAPK8
MIR106B
MIR107
MIR122
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR15A
MIR15B
MIR17
MIR199A1
MIR199A2
MIR19B1
MIR19B2
MIR205
MIR206
MIR20B
MIR214
MIR222
MIR25
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7I
OPTN
RARS1
SUMO2
TSNAX
Entrez ID
406885
9255
HPRD ID
04676
Ensembl ID
ENSG00000199030
ENSG00000164022
Uniprot IDs
B4DNK3
Q12904
PDB IDs
1E7Z
1EUJ
1FL0
4R3Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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