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MIRLET7C and EDC4
Data Source:
BioGRID
(unspecified method)
MIRLET7C
EDC4
Description
microRNA let-7c
enhancer of mRNA decapping 4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Cytoplasm
Extracellular Exosome
Extracellular Vesicle
P-body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
MRNA Binding Involved In Posttranscriptional Gene Silencing
Protein Binding
Biological Process
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-8 Production
Gene Silencing By MiRNA
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Receptor Signaling Pathway Via STAT
Biological_process
Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Exonucleolytic Catabolism Of Deadenylated MRNA
Pathways
mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS
HDL cholesterol (
21347282
)
Metabolic syndrome (
22399527
)
Refractive error (
32231278
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
96 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
ATXN2L
C1QBP
CHERP
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI1
MSI2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PLOD1
PTBP1
PTBP3
PUF60
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RBM4B
RBMS2
RTCA
RTCB
SART3
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
TUT4
TUT7
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
38 interacting genes:
CCL5
CDC42
EIF2AK2
FBLN1
GIT2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR122
MIR128-2
MIR141
MIR15B
MIR199A1
MIR200A
MIR200B
MIR200C
MIR205
MIR20A
MIR21
MIR214
MIR222
MIR29C
MIR34A
MIR34C
MIR363
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A3
MIRLET7C
MIRLET7D
MIRLET7E
SUMO2
YTHDC1
Entrez ID
406885
23644
HPRD ID
06911
Ensembl ID
ENSG00000199030
ENSG00000038358
Uniprot IDs
Q6P2E9
PDB IDs
Enriched GO Terms of Interacting Partners
?
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Tagcloud (Difference)
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Tagcloud (Intersection)
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