LTK and MTMR14

Data Source:
BioGRID (two hybrid)

		LTK	MTMR14
Description		leukocyte receptor tyrosine kinase	myotubularin related protein 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Receptor Complex	Ruffle Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Phosphatidylinositol-3-phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Protein Phosphorylation Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Cell Population Proliferation Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Neuron Projection Development Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Cell Population Proliferation Negative Regulation Of Apoptotic Process Regulation Of Neuron Differentiation Cellular Response To Retinoic Acid	Phosphatidylinositol Biosynthetic Process Macroautophagy Peptidyl-tyrosine Dephosphorylation
Pathways			Macroautophagy Synthesis of PIPs at the plasma membrane
Drugs		Fostamatinib
Diseases
GWAS		High density lipoprotein cholesterol levels ( 31928498) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Lymphocyte percentage of white cells ( 32888494) Type 2 diabetes ( 30297969) Urinary albumin excretion (no hypertensive medication) ( 30220432)	Daytime sleep phenotypes ( 27126917)
Interacting Genes		6 interacting genes: CBL DUSP6 MTMR14 PIK3C2B PTPN1 SHC1	8 interacting genes: APP ENO3 EPHA1 EPHA7 EPHB2 LTK TIE1 TP53BP2
Entrez ID		4058	64419
HPRD ID		01052	08654
Ensembl ID		ENSG00000062524	ENSG00000163719
Uniprot IDs		P29376	Q8NCE2 Q8WYY9
PDB IDs
Enriched GO Terms of Interacting Partners?
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