AQP8 and PLP2

Data Source:
BioGRID (two hybrid)

		AQP8	PLP2
Description		aquaporin 8	proteolipid protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Mitochondrial Membrane Apical Part Of Cell	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Water Channel Activity	Protein Binding Ion Transmembrane Transporter Activity Chemokine Binding
	Biological Process	Water Transport Transmembrane Transport Cellular Response To CAMP	Ion Transport Chemotaxis Cytokine-mediated Signaling Pathway Ion Transmembrane Transport
Pathways		Detoxification of Reactive Oxygen Species Passive transport by Aquaporins
Drugs
Diseases
GWAS		Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 27400856)	Platelet distribution width ( 32888494)
Interacting Genes		6 interacting genes: CYBC1 PLP2 PLPP6 SERP1 STX12 TMEM120B	74 interacting genes: AQP2 AQP3 AQP8 ARFIP2 ASGR2 ATP5PF BCAP31 BIK BNIP3 CCR1 CD53 CD79A CERS4 CIAO2A CLDN5 CLN8 CPLX4 CRB3 CREB3L1 CYB561 CYBC1 CYBRD1 DARS2 DLGAP4 DNAJC1 EBP ELOVL5 ELP1 EVI2A FAM209A FAM210B FATE1 FCER1G FNDC9 GPR151 GPX8 HSBP1L1 HSD17B11 HSD17B13 KASH5 LHFPL1 LHFPL5 LMNA LRRC4C MGST3 NDRG4 PACC1 PDZK1IP1 PIGP PSCA PTGES PVR REEP4 RETREG3 RNF5 SAR1A SCN3B SGPL1 SHBG SLC14A2 SLC18A1 SLC2A13 SLC35C2 SPG21 SPN THAP4 TM4SF19 TMEM14B TMEM31 TMEM51 TMEM79 TMPRSS2 TMX2 VKORC1
Entrez ID		343	5355
HPRD ID		04778	02121
Ensembl ID		ENSG00000103375	ENSG00000102007
Uniprot IDs		O94778	A0A024QYW3 Q04941
PDB IDs
Enriched GO Terms of Interacting Partners?
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