MED11 and NME7

Data Source:
BioGRID (two hybrid)

		MED11	NME7
Description		mediator complex subunit 11	NME/NM23 family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Mediator Complex	Centrosome Cytosol
	Molecular Function	Transcription Coregulator Activity Protein Binding Ubiquitin Protein Ligase Activity	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process
Pathways		PPARA activates gene expression Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS			Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)
Interacting Genes		13 interacting genes: ABI2 APP CCDC120 GCSH MED22 MED8 MED9 NDEL1 NME7 SGF29 SSC5D SYCE2 USHBP1	75 interacting genes: AMOTL2 ARHGAP9 BTBD6 C1orf189 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620
Entrez ID		400569	29922
HPRD ID		14709	11394
Ensembl ID		ENSG00000161920	ENSG00000143156
Uniprot IDs		I3L3E8 Q9P086	A0A024R8Z7 Q9Y5B8
PDB IDs
Enriched GO Terms of Interacting Partners?
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