NME7 and RUBCN

Data Source:
BioGRID (two hybrid)

		NME7	RUBCN
Description		NME/NM23 family member 7	rubicon autophagy regulator
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Left-handedness ( 32989287) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)
Interacting Genes		75 interacting genes: AMOTL2 ARHGAP9 BTBD6 C1orf189 CARD10 CBY2 CCDC136 CCDC33 CCDC88B CCHCR1 CDC42EP2 CEP72 DDIT4L DDX1 DISC1 DNAI7 EFHC2 FKBP6 FLOT1 FOSL1 FOSL2 GATAD2B GLIS2 GOLGA2 GSC2 HAUS8 IKZF1 IKZF3 INCA1 ISY1-RAB43 KRT18 KRT75 LNX1 MAP4K4 MED11 MED30 MEI4 MEOX2 MYOT NAB2 NEFL NFKBIL1 NIF3L1 NME4 NT5C2 OFD1 PAX4 PIAS2 PICK1 POU6F2 PROSER3 PSMA1 REL RUBCN SHTN1 SNAPIN SNX32 SYCE1 TCF4 TCHP TEKT1 TEPSIN THAP10 TNIP1 TNNI2 TRIM27 TRIM48 TUFT1 YWHAQ ZBTB48 ZNF23 ZNF263 ZNF343 ZNF526 ZNF620	15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648
Entrez ID		29922	9711
HPRD ID		11394	11069
Ensembl ID		ENSG00000143156	ENSG00000145016
Uniprot IDs		A0A024R8Z7 Q9Y5B8	Q8N4U6 Q92622
PDB IDs			6WCW
Enriched GO Terms of Interacting Partners?
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