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NME7 and CDC42EP2
Data Source:
BioGRID
(two hybrid)
NME7
CDC42EP2
Description
NME/NM23 family member 7
CDC42 effector protein 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Centrosome
Cytosol
Cytoplasm
Cytosol
Cytoskeleton
Plasma Membrane
Endomembrane System
Microtubule Cytoskeleton
Membrane
Phagocytic Vesicle
Molecular Function
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Opioid Peptide Activity
GTPase Activator Activity
Protein Binding
Small GTPase Binding
Biological Process
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
Actin Filament Organization
Rho Protein Signal Transduction
Regulation Of Cell Shape
Actin Cytoskeleton Organization
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Pseudopodium Assembly
Positive Regulation Of Protein-containing Complex Assembly
Positive Regulation Of GTPase Activity
Cellular Response To Interferon-gamma
Pathways
Recruitment of mitotic centrosome proteins and complexes
Recruitment of NuMA to mitotic centrosomes
MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS
Coronary artery disease (
29212778
)
D-dimer levels (
21502573
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Left-handedness (
32989287
)
Pulse pressure (
27841878
30578418
)
QT interval (
30679814
)
Systolic blood pressure (
27841878
30578418
)
Venous thromboembolism (
21980494
22672568
)
Acne (severe) (
24927181
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
27863252
)
Interacting Genes
75 interacting genes:
AMOTL2
ARHGAP9
BTBD6
C1orf189
CARD10
CBY2
CCDC136
CCDC33
CCDC88B
CCHCR1
CDC42EP2
CEP72
DDIT4L
DDX1
DISC1
DNAI7
EFHC2
FKBP6
FLOT1
FOSL1
FOSL2
GATAD2B
GLIS2
GOLGA2
GSC2
HAUS8
IKZF1
IKZF3
INCA1
ISY1-RAB43
KRT18
KRT75
LNX1
MAP4K4
MED11
MED30
MEI4
MEOX2
MYOT
NAB2
NEFL
NFKBIL1
NIF3L1
NME4
NT5C2
OFD1
PAX4
PIAS2
PICK1
POU6F2
PROSER3
PSMA1
REL
RUBCN
SHTN1
SNAPIN
SNX32
SYCE1
TCF4
TCHP
TEKT1
TEPSIN
THAP10
TNIP1
TNNI2
TRIM27
TRIM48
TUFT1
YWHAQ
ZBTB48
ZNF23
ZNF263
ZNF343
ZNF526
ZNF620
11 interacting genes:
ARHGAP26
CASS4
CDC42
COX5B
NEDD9
NME7
PICK1
RHOQ
SEPTIN6
SEPTIN7
SNCA
Entrez ID
29922
10435
HPRD ID
11394
09363
Ensembl ID
ENSG00000143156
ENSG00000149798
Uniprot IDs
A0A024R8Z7
Q9Y5B8
O14613
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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