ARL1 and GCC1

Data Source:
BioGRID (two hybrid)

		ARL1	GCC1
Description		ADP ribosylation factor like GTPase 1	GRIP and coiled-coil domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol
	Molecular Function	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Protein Binding Small GTPase Binding
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)
Interacting Genes		8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	64 interacting genes: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 DISC1 DNAJA3 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX ICA1L IKBKG ITSN1 KATNAL1 KDM1A KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PPP1R18 PPP1R27 PRPF18 RUNX1 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276
Entrez ID		400	79571
HPRD ID		04574	07599
Ensembl ID		ENSG00000120805	ENSG00000179562
Uniprot IDs		B4DZG7 P40616	A4D0Z4 Q96CN9
PDB IDs		1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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