ARL1 and GOLGA4

Data Source:
BioGRID (x-ray crystallography, pull down, two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		ARL1	GOLGA4
Description		ADP ribosylation factor like GTPase 1	golgin A4
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Extracellular Exosome
	Molecular Function	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Protein Binding Small GTPase Binding GTPase Binding
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi	Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension Golgi Vesicle Transport
Pathways		Retrograde transport at the Trans-Golgi-Network	Retrograde transport at the Trans-Golgi-Network Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Autism spectrum disorder or schizophrenia ( 28540026) Pulse pressure ( 30578418) Subjective response to lithium treatment ( 26503763)
Interacting Genes		8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	8 interacting genes: APP ARL1 ARL3 MACF1 RAB6A SERPINB5 TNIK TRAF3IP1
Entrez ID		400	2803
HPRD ID		04574	03941
Ensembl ID		ENSG00000120805	ENSG00000144674
Uniprot IDs		B4DZG7 P40616	Q13439 Q49A56
PDB IDs		1UPT 4DCN 5EE5 5J5C	1R4A 1UPT
Enriched GO Terms of Interacting Partners?
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