GCC1 and LCA5

Data Source:
BioGRID (two hybrid)

		GCC1	LCA5
Description		GRIP and coiled-coil domain containing 1	lebercilin LCA5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Trans Cisterna Golgi Membrane Golgi Apparatus Cytosol	Cilium Axoneme Photoreceptor Connecting Cilium Ciliary Basal Body
	Molecular Function	Protein Binding Small GTPase Binding	Protein Binding Protein-containing Complex Binding
	Biological Process		Intraciliary Transport Photoreceptor Cell Maintenance
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases			Leber congenital amaurosis (LCR)
GWAS		Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Refractive error ( 32231278) Type 2 diabetes ( 26818947 22158537 30718926)	Glucose homeostasis traits ( 25524916) Hoarding ( 21302353) Presence of antiphospholipid antibodies ( 23509613)
Interacting Genes		64 interacting genes: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC33 CCDC85B CEP57 CEP70 COIL CPSF7 DISC1 DNAJA3 FAM83A FBF1 FBXO28 FIGNL1 FOSL1 GAS8 GLI1 GOLGA2 GTF2I HDX ICA1L IKBKG ITSN1 KATNAL1 KDM1A KIAA0753 KIAA1217 KIF5B LCA5 LZTS2 MCRS1 MED4 MEOX1 MID2 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PPP1R18 PPP1R27 PRPF18 RUNX1 SMARCD1 SPOP TFIP11 TLE5 TP53BP2 TRIM29 TRIM50 USHBP1 UTP14C XIAP ZC4H2 ZFP90 ZNF276	6 interacting genes: GCC1 RCOR3 SRPK2 SUFU TFIP11 TXLNA
Entrez ID		79571	167691
HPRD ID		07599	10791
Ensembl ID		ENSG00000179562	ENSG00000135338
Uniprot IDs		A4D0Z4 Q96CN9	A0A384MDJ7 Q86VQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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