ARL1 and COPG2

Data Source:
HPRD (in vivo)

		ARL1	COPG2
Description		ADP ribosylation factor like GTPase 1	COPI coat complex subunit gamma 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Trans-Golgi Network Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol COPI Vesicle Coat Transport Vesicle Growth Cone
	Molecular Function	GTPase Activity GTP Binding Enzyme Activator Activity Protein Domain Specific Binding Metal Ion Binding	Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Golgi Organization Toxin Metabolic Process Vesicle-mediated Transport Activation Of Phospholipase D Activity Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Organelle Transport Along Microtubule
Pathways		Retrograde transport at the Trans-Golgi-Network	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS		Lung cancer in never smokers ( 28604730) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Pancreatic cancer ( 25086665) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		8 interacting genes: ARFIP2 COPG2 DRD2 GCC1 GCC2 GOLGA1 GOLGA4 SCOC	12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10
Entrez ID		400	26958
HPRD ID		04574	05074
Ensembl ID		ENSG00000120805	ENSG00000158623
Uniprot IDs		B4DZG7 P40616	A0A140VK12 Q9NSM7 Q9UBF2
PDB IDs		1UPT 4DCN 5EE5 5J5C
Enriched GO Terms of Interacting Partners?
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