LCP1 and NLGN4X

Data Source:
BioGRID (proximity labelling technology)

		LCP1	NLGN4X
Description		lymphocyte cytosolic protein 1	neuroligin 4 X-linked
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GO Annotations	Cellular Component	Stress Fiber Ruffle Phagocytic Cup Podosome Extracellular Space Cytoplasm Cytosol Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Cell Junction Filopodium Actin Filament Bundle Ruffle Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse
	Molecular Function	Actin Binding Integrin Binding Calcium Ion Binding Identical Protein Binding Actin Filament Binding GTPase Binding	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	T Cell Activation Involved In Immune Response Protein Kinase A Signaling Cell Migration Extracellular Matrix Disassembly Cortical Actin Cytoskeleton Organization Animal Organ Regeneration Regulation Of Intracellular Protein Transport Interleukin-12-mediated Signaling Pathway Wound Healing, Spreading Of Cells Actin Filament Bundle Assembly Actin Filament Network Formation Actin Crosslink Formation Positive Regulation Of Podosome Assembly	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly
Pathways		Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases			Non-syndromic X-linked mental retardation
GWAS		Blood protein levels ( 30072576 28240269) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Non-alcoholic fatty liver disease histology (other) ( 23213074) Platelet count ( 32888494) Platelet distribution width ( 32888494) Systemic lupus erythematosus ( 26502338)	Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)
Interacting Genes		5 interacting genes: AIF1 ATXN2 CNN3 GCA PRKACA	2 interacting genes: DLG4 DLGAP2
Entrez ID		3936	57502
HPRD ID		01082	02336
Ensembl ID		ENSG00000136167	ENSG00000146938
Uniprot IDs		A0A024RDT4 P13796	A0A024RBV0 A8K4S1 B3KP11 Q8N0W4
PDB IDs		2D85 5JOJ 5JOL	2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
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