NLGN4X and DLGAP2

Data Source:
HPRD (in vitro)

		NLGN4X	DLGAP2
Description		neuroligin 4 X-linked	DLG associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse	Neurofilament Plasma Membrane Postsynaptic Density Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly	Neuron-neuron Synaptic Transmission Regulation Of Postsynaptic Neurotransmitter Receptor Activity
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)	Bipolar disorder ( 31043756) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		2 interacting genes: DLG4 DLGAP2	19 interacting genes: ABI2 ADRB1 CYSRT1 DGCR6 DLG2 DLG3 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 MAGI2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1 UBASH3B
Entrez ID		57502	9228
HPRD ID		02336	09258
Ensembl ID		ENSG00000146938	ENSG00000198010
Uniprot IDs		A0A024RBV0 A8K4S1 B3KP11 Q8N0W4	A0A1B0GTN4
PDB IDs		2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
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