LBR and FNBP4

Data Source:
HPRD (in vitro)

		LBR	FNBP4
Description		lamin B receptor	formin binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Nuclear Speck
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Delta14-sterol Reductase Activity Chromo Shadow Domain Binding NADPH Binding	Protein Binding
	Biological Process	Cholesterol Biosynthetic Process Sterol Biosynthetic Process Neutrophil Differentiation
Pathways		Cholesterol biosynthesis Initiation of Nuclear Envelope (NE) Reformation Regulation of MECP2 expression and activity
Drugs
Diseases		HEM skeletal dysplasia; Greenberg dysplasia Pelger-Huet anomaly
GWAS		Delirium ( 29631748) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Alcohol use disorder (consumption score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Free thyroxine concentration ( 30367059) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Medication use (antiglaucoma preparations and miotics) ( 31015401) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)
Interacting Genes		12 interacting genes: AKAP8L CBX3 CBX5 CD81 FNBP4 H4C14 LMNB1 MECP2 PRM1 SRPK1 SRPK2 YWHAG	10 interacting genes: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1
Entrez ID		3930	23360
HPRD ID		02488	10996
Ensembl ID		ENSG00000143815	ENSG00000109920
Uniprot IDs		Q14739	Q8N3X1
PDB IDs		2DIG
Enriched GO Terms of Interacting Partners?
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