FNBP4 and PLXNA2

Data Source:
HPRD (two hybrid)

		FNBP4	PLXNA2
Description		formin binding protein 4	plexin A2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Speck	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Semaphorin Receptor Activity Identical Protein Binding
	Biological Process		Somitogenesis Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways			Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
Drugs
Diseases
GWAS		Alcohol use disorder (consumption score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Free thyroxine concentration ( 30367059) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Medication use (antiglaucoma preparations and miotics) ( 31015401) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)	Adolescent idiopathic scoliosis ( 31417091) Bitter alcoholic beverage consumption ( 31046077) Cardiac hypertrophy ( 21348951) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) General risk tolerance (MTAG) ( 30643258) Lung cancer in never smokers ( 28604730) Manganese levels ( 26025379) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		10 interacting genes: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1	6 interacting genes: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L
Entrez ID		23360	5362
HPRD ID		10996	03033
Ensembl ID		ENSG00000109920	ENSG00000076356
Uniprot IDs		Q8N3X1	O75051
PDB IDs			3Q3J
Enriched GO Terms of Interacting Partners?
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