FNBP4 and LBR

Data Source:
HPRD (in vitro)

		FNBP4	LBR
Description		formin binding protein 4	lamin B receptor
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Speck	Nucleus Nuclear Envelope Nuclear Inner Membrane Integral Component Of Nuclear Inner Membrane Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Protein Binding	DNA Binding RNA Binding Protein Binding Lamin Binding Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Delta14-sterol Reductase Activity Chromo Shadow Domain Binding NADPH Binding
	Biological Process		Cholesterol Biosynthetic Process Sterol Biosynthetic Process Neutrophil Differentiation
Pathways			Cholesterol biosynthesis Initiation of Nuclear Envelope (NE) Reformation Regulation of MECP2 expression and activity
Drugs
Diseases			HEM skeletal dysplasia; Greenberg dysplasia Pelger-Huet anomaly
GWAS		Alcohol use disorder (consumption score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Free thyroxine concentration ( 30367059) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Medication use (antiglaucoma preparations and miotics) ( 31015401) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)	Delirium ( 29631748) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		10 interacting genes: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1	12 interacting genes: AKAP8L CBX3 CBX5 CD81 FNBP4 H4C14 LMNB1 MECP2 PRM1 SRPK1 SRPK2 YWHAG
Entrez ID		23360	3930
HPRD ID		10996	02488
Ensembl ID		ENSG00000109920	ENSG00000143815
Uniprot IDs		Q8N3X1	Q14739
PDB IDs			2DIG
Enriched GO Terms of Interacting Partners?
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