FAM221B and LCE2C

Data Source:
BioGRID (two hybrid)

		FAM221B	LCE2C
Description		family with sequence similarity 221 member B	late cornified envelope 2C
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Multiple sclerosis ( 31604244)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		14 interacting genes: ANKRD11 CCDC13 CYSRT1 EFHC2 GSC2 KPRP KRT35 KRTAP10-8 KRTAP13-1 LBX1 LCE2C LZTS2 PLSCR2 TRIM50	84 interacting genes: ADAMTSL4 ALPP C1orf94 CATSPER1 CCDC125 CHIC2 CRCT1 CREB5 CYP21A2 CYSRT1 EFEMP1 EFEMP2 EFNA3 FAM221B HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3D LCE4A LCE5A MACO1 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PCSK5 PIAS2 PTPMT1 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 TAP1 TGFB1 TM7SF2 TRIM42 UBE2I VASN VWC2 XAGE3
Entrez ID		392307	353140
HPRD ID		16675	13972
Ensembl ID		ENSG00000204930	ENSG00000187180
Uniprot IDs		A6H8Z2	Q5TA81
PDB IDs
Enriched GO Terms of Interacting Partners?
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