FAM221B and TRIM50

		FAM221B	TRIM50
Description		family with sequence similarity 221 member B	tripartite motif containing 50
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process		Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Multiple sclerosis ( 31604244)	Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		14 interacting genes: ANKRD11 CCDC13 CYSRT1 EFHC2 GSC2 KPRP KRT35 KRTAP10-8 KRTAP13-1 LBX1 LCE2C LZTS2 PLSCR2 TRIM50	40 interacting genes: ARHGAP45 CDK18 CLK2 EFHC2 EPM2AIP1 FAM221B GCC1 HDAC6 IQUB KLHL2 L3MBTL2 LNX1 MEOX2 PIAS2 PLA2G6 RAD23A RSPH14 SNAI1 SPG21 SRC TEPSIN TRAF2 TRIM27 TSGA10IP TSSK3 UBASH3A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2N UBTD1 USP2 XAF1 ZNF438 ZNF620
Entrez ID		392307	135892
HPRD ID		16675	15566
Ensembl ID		ENSG00000204930	ENSG00000146755
Uniprot IDs		A6H8Z2	B7ZLG2 Q2M204 Q86XT4
PDB IDs
Enriched GO Terms of Interacting Partners?
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