LCE2C and KRTAP5-3

Data Source:
BioGRID (two hybrid)

		LCE2C	KRTAP5-3
Description		late cornified envelope 2C	keratin associated protein 5-3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Keratin Filament
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Keratinization	Keratinization
Pathways		Formation of the cornified envelope	Keratinization
Drugs			Beta-D-Glucose
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		84 interacting genes: ADAMTSL4 ALPP C1orf94 CATSPER1 CCDC125 CHIC2 CRCT1 CREB5 CYP21A2 CYSRT1 EFEMP1 EFEMP2 EFNA3 FAM221B HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2D LCE3A LCE3B LCE3D LCE4A LCE5A MACO1 NBPF19 NECTIN2 NOTCH2NLA NTAQ1 NUFIP2 OTX1 PCSK5 PIAS2 PTPMT1 RGS17 RGS20 RNF4 SLC39A7 SMCP SPRY1 TAP1 TGFB1 TM7SF2 TRIM42 UBE2I VASN VWC2 XAGE3	43 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP11-1 KRTAP15-1 KRTAP4-2 KRTAP5-1 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2C LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 SMCP
Entrez ID		353140	387266
HPRD ID		13972	12395
Ensembl ID		ENSG00000187180	ENSG00000196224
Uniprot IDs		Q5TA81	Q6L8H2
PDB IDs
Enriched GO Terms of Interacting Partners?
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