RPSA and RNF114

Data Source:
BioGRID (two hybrid)

		RPSA	RNF114
Description		ribosomal protein SA	ring finger protein 114
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome	Nucleus Cytosol Plasma Membrane
	Molecular Function	Virus Receptor Activity RNA Binding Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Viral Transcription Viral Entry Into Host Cell	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Multicellular Organism Development Spermatogenesis Cell Differentiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Antigen processing: Ubiquitination & Proteasome degradation
Drugs		Tigapotide Copper
Diseases
GWAS		Dentate gyrus volume x schizophrenia interaction ( 31155012)	Gut microbiota (beta diversity) ( 27723756) Inflammatory skin disease ( 25574825) Psoriasis ( 25903422 20953189 25574825 23143594) Psoriasis vulgaris ( 26626624) Systemic lupus erythematosus ( 24871463)
Interacting Genes		31 interacting genes: ABCD1 ACADVL ACD ANKH CALM2 CBX5 CCDC13 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD HSPB1 IL7R ILRUN ITGA6 KARS1 LAMA2 LINC01554 NKX3-1 PEA15 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3	29 interacting genes: AK5 BMI1 EVI2A MAP3K1 MAPK3 RNF38 RPSA SMURF1 TRAF4 TRAF6 TRAIP TRIM52 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2DNL UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2K UBE2L3 UBE2U UBE2W UEVLD XAF1
Entrez ID		3921	55905
HPRD ID		01038	10329
Ensembl ID		ENSG00000168028	ENSG00000124226
Uniprot IDs		A0A024R2L6 A0A0C4DG17 P08865	Q9Y508
PDB IDs		3BCH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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