KRTAP10-4 and RSPO2

Data Source:
BioGRID (two hybrid)

		KRTAP10-4	RSPO2
Description		keratin associated protein 10-4	R-spondin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Extracellular Region Cell Surface
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding Heparin Binding
	Biological Process	Keratinization	Osteoblast Differentiation Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Bone Mineralization Embryonic Forelimb Morphogenesis Embryonic Hindlimb Morphogenesis Negative Regulation Of Odontogenesis Of Dentin-containing Tooth Limb Development Lung Growth Epithelial Tube Branching Involved In Lung Morphogenesis Trachea Cartilage Morphogenesis Dopaminergic Neuron Differentiation Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways			Regulation of FZD by ubiquitination
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421)	Acute lymphoblastic leukemia (childhood) ( 22076464) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Intake of total sugars ( 31005972) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)
Interacting Genes		10 interacting genes: CATSPER1 E4F1 HOXA1 IGSF8 JOSD1 RSPO2 WT1 ZNF32 ZNF625 ZSCAN26	19 interacting genes: CATSPER1 CYSRT1 HOXA1 JMJD6 KRTAP10-1 KRTAP10-4 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP12-3 LGR4 LGR5 PLEKHF2 RNF43 SLC39A7 SUV39H1 ZNF330 ZNF837 ZNRF3
Entrez ID		386672	340419
HPRD ID		11190	17536
Ensembl ID		ENSG00000215454	ENSG00000147655
Uniprot IDs			B3KVP3 Q6UXX9
PDB IDs
Enriched GO Terms of Interacting Partners?
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