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KPNA1 and LMNB1
Data Source:
BioGRID
(two hybrid)
KPNA1
LMNB1
Description
karyopherin subunit alpha 1
lamin B1
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Pore
Nucleoplasm
Cytoplasm
Cytosol
Postsynaptic Density
Dendrite
Host Cell
Glutamatergic Synapse
Nucleus
Nuclear Envelope
Nuclear Inner Membrane
Lamin Filament
Nucleoplasm
Membrane
Nuclear Matrix
Nuclear Membrane
Molecular Function
Protein Binding
Nuclear Localization Sequence Binding
Nuclear Import Signal Receptor Activity
Structural Molecule Activity
Protein Binding
Phospholipase Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of DNA Recombination
Apoptotic DNA Fragmentation
NLS-bearing Protein Import Into Nucleus
Skeletal Muscle Satellite Cell Proliferation
Satellite Cell Activation Involved In Skeletal Muscle Regeneration
Modulation By Virus Of Host Cellular Process
Regulation Of Apoptotic Process
Regulation Of Canonical Wnt Signaling Pathway
Intracellular Transport Of Virus
Postsynapse To Nucleus Signaling Pathway
Interleukin-12-mediated Signaling Pathway
Pathways
ISG15 antiviral mechanism
Apoptosis induced DNA fragmentation
Integration of provirus
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Vpr-mediated nuclear import of PICs
Inhibition of nitric oxide production
Meiotic synapsis
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Breakdown of the nuclear lamina
Depolymerisation of the Nuclear Lamina
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS
Calcium levels (
20705733
)
LDL cholesterol (
30275531
)
LDL cholesterol levels (
28334899
)
Mean corpuscular hemoglobin (
32888494
)
Parkinson's disease or first degree relation to individual with Parkinson's disease (
31701892
)
Blood protein levels (
30072576
29875488
)
Body fat percentage (
31752434
)
Parkinson's disease (motor and cognition) (
22658654
)
Interacting Genes
45 interacting genes:
ANP32A
ANP32B
ARNT
BCAR3
CDKN1B
CLK4
CRADD
CSE1L
ELAVL1
EPAS1
FOSL1
GOPC
GTF2IRD1
H2BC21
H3-4
HDAC6
HIF1A
IL1RAP
KPNB1
LEF1
LINC01554
LMNB1
LMO4
MACROD1
MDM2
NMNAT1
NOSIP
NUP50
NUP54
NUP62
ORC4
PAX5
PKM
POLR3C
RAG1
RANBP2
RUNX1T1
SENP2
SKP2
SRP19
STAT1
STAT3
TAF9
UBR5
USP1
44 interacting genes:
ABCG8
ATF4
CASP3
CASP6
CCDC88B
CDK1
CENPH
DMAP1
FAM169A
GABARAP
GIT2
GZMA
GZMB
KPNA1
KPNA5
KPNA6
LBR
LMNA
LMNB2
M1AP
MAP1LC3A
MAP1LC3C
MBIP
MELK
PIAS2
PIH1D2
PLEC
PPP1R13B
PRKCA
PRKCB
PRKCD
PRPH
PTEN
RNF123
SERPINA3
SNAPIN
SRPK2
SUMO4
TMPO
TOR1AIP1
TP53BP2
UBE2I
URB2
YWHAQ
Entrez ID
3836
4001
HPRD ID
02819
01036
Ensembl ID
ENSG00000114030
ENSG00000113368
Uniprot IDs
B3KXZ2
P52294
B4DZT3
P20700
PDB IDs
2JDQ
3TJ3
4B18
6WX9
2KPW
3JT0
3TYY
3UMN
5VVX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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