IMPA2 and CCT6A

Data Source:
BioGRID (two hybrid)

		IMPA2	CCT6A
Description		inositol monophosphatase 2	chaperonin containing TCP1 subunit 6A
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Extracellular Exosome
	Molecular Function	Protein Binding Inositol Monophosphate 1-phosphatase Activity Protein Homodimerization Activity Metal Ion Binding Inositol Monophosphate 3-phosphatase Activity Inositol Monophosphate 4-phosphatase Activity	RNA Binding Protein Binding ATP Binding Protein Folding Chaperone Unfolded Protein Binding WD40-repeat Domain Binding
	Biological Process	Inositol Metabolic Process Inositol Biosynthetic Process Phosphate-containing Compound Metabolic Process Signal Transduction Inositol Phosphate Metabolic Process Phosphatidylinositol Phosphorylation Inositol Phosphate Dephosphorylation	Protein Folding Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body
Pathways		Synthesis of IP2, IP, and Ins in the cytosol	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs		Lithium cation Lithium citrate Lithium succinate Lithium carbonate
Diseases
GWAS		Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Hemoglobin ( 32888494) Obsessive-compulsive disorder or autism spectrum disorder ( 28641744) Stroke ( 17434096)	Coronary artery disease ( 33020668) Estimated glomerular filtration rate ( 31015462) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Systolic blood pressure ( 30224653)
Interacting Genes		6 interacting genes: CCT6A HERPUD1 IMPA1 SLC44A3 TNFRSF14 UBA3	15 interacting genes: DUX4 ERCC6 IMPA2 KDM5A LINC01554 MLX MYBPC2 PARP4 PTEN SGCG SUMO2 SUMO4 SUPT16H TRIM31 TTN
Entrez ID		3613	908
HPRD ID		09329	00089
Ensembl ID		ENSG00000141401	ENSG00000146731
Uniprot IDs		O14732	A0A024RDL1 P40227
PDB IDs		2CZH 2CZI 2CZK 2DDK 2FVZ	6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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