IL13RA2 and BRMS1

Data Source:
BioGRID (two hybrid)

		IL13RA2	BRMS1
Description		interleukin 13 receptor subunit alpha 2	BRMS1 transcriptional repressor and anoikis regulator
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex	Nucleus Nucleoplasm Cytoplasm Sin3-type Complex
	Molecular Function	Cytokine Receptor Activity Protein Binding Cytokine Binding	Protein Binding Histone Deacetylase Binding NF-kappaB Binding
	Biological Process	Negative Regulation Of Immunoglobulin Production Immunoglobulin Mediated Immune Response Cytokine-mediated Signaling Pathway Negative Regulation Of Mast Cell Degranulation	Negative Regulation Of Transcription By RNA Polymerase II Apoptotic Process Histone Deacetylation Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Deacetylation Positive Regulation Of Anoikis
Pathways		Interleukin-4 and Interleukin-13 signaling	HDACs deacetylate histones Potential therapeutics for SARS
Drugs		AER001
Diseases
GWAS			Bipolar disorder ( 21926972 31043756)
Interacting Genes		17 interacting genes: AKT1 BAG4 BRMS1 CASP8 EGFR ERBB2 ESR2 IGF1R IL13 IL4 IL4R NOTCH2 PALB2 PAX2 PIK3CA PLPP6 RB1CC1	49 interacting genes: ANGPTL4 APP ARID4A BEX2 BRMS1L CEP70 CSNK2A1 CYTOR DIRAS3 DNAJB1 DNAJB6 E2F1 EEF1A1 EP300 GOLGB1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC5 HDAC6 HSP90AA1 HSPA4 IL13RA2 ING1 KLK9 KPNA5 LRIF1 LYPD3 MCRS1 MRC2 NMI PFDN5 PSMC3IP RBBP4 RBBP7 RBP1 RELA SAP30 SIN3A SMARCE1 SMTN SNAI1 SNX6 SPOP SUDS3 TAF1 THRSP UBE2D1
Entrez ID		3598	25855
HPRD ID		02132	05879
Ensembl ID		ENSG00000123496	ENSG00000174744
Uniprot IDs		Q14627	G5E9I4 Q9HCU9
PDB IDs		3LB6	2XUS 4AUV
Enriched GO Terms of Interacting Partners?
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